Current Issue
Volume: 122
Number: 1
Index: January 2010
Clinical Focus: Emergency Medicine
Call For Papers
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March 2010
Clinical Focus: Deep Venous Thrombosis, Cardiovascular Events, Differential Diagnosis, and Gastrointestinal Disorders
Gastrointestinal:
  • Gastroesophageal reflux disease
  • Ulcerative colitis
  • Crohn's disease
  • Spastic colon
  • GI tract erosion
  • Bariatric surgery
  • Laparoscopic band surgery
  • Short bowel syndrome and recombinant human growth hormone
  • Malabsorption syndrome
  • Parenteral nutrition
  • Screening for pelvic dyssynergia in chronic constipation
  • Cyclic vomiting syndrome
  • Cell transplantation: minimally invasive surgery
  • Sources for hepatocytes for transplantation
  • Future directions in endoscopic sedation
  • The role of anesthesia in endoscopy
  • Advances in celiac disease
  • Enteroscopy for inflammatory disorders
  • CLDs: Markers of disease progression
  • GERD: PPI failure
  • Preventing colorectal cancer in inflammatory bowel disease
  • Autoimmune disorders of the pancreas and biliary tract
  • Bariatrics for the endoscopist: bypasses and detours
  • Colonoscopic cancer screening in 2010
  • Common approaches to pelvic floor abnormalities
  • Detecting and managing colonic dysplasia in IBD: current and future practices
  • Gastrointestinal surgery in the elderly
  • Hepatic resection for liver masses
  • Optional management of anticoagulation
  • Management of hepatitis C non-responders and relapsers
  • Multimodality detection and management of Barrett's and dysplasia
  • NASH and comorbidities
  • New and emerging approaches to the management of IBS
  • NOTES single-port access surgery
  • Pancreatic cancer screening
  • Predicting and treating variceal hemorrhage
  • Advances in endoscopic imaging
  • Clinical HPB/upper GI
  • Endoscopic sedation and monitoring issues in 2010
  • HCV therapy advances
  • New developments in eosinophilic esophagitis
Cardiovascular:
  • Long-term outcomes of drug-eluting versus bare-metal stents in underrepresented populations: results from the Linked NCDR and CMS database
  • Antithrombotic strategy during PCI in NSTEMI: Update from ACTION registry GWTG
  • Timing of in-hospital CABG in relationship to mortality for ACS patients: NCDR ACTION registry
  • Limitations of using cardiac catheterization rates as a quality measure for non-ST-segment elevation MI
  • STEMI care and outcomes
  • High-risk features of carotid artery stent patients: preliminary results from the CARE registry
  • Secondary prevention therapies among patients with nonobstructive CAD
  • Regional variations of primary prevention implantable cardioverter-defibrillators
  • High-dose statins usage before PCI
  • Embolic Protection in Patients With Atrial Fibrillation (PROTECT AF) trial and Watchman group
  • JUPITER trial and rosuvastatin reducing risk of thromboembolism
  • Combination treatment in atrial fibrillation
  • Polypill usage with statins, aspirin, and folic acid
  • Benefits of renal sympathetic nerve ablation
  • Use of relaxin in acute heart failure
  • Detecting DVT: venous access in the emergency department
  • DVT prevention in the at-risk patient population
  • DVT prevention in critically ill patients
Submission deadline: January 04
Fast-Track deadline: January 20
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Fast-Track peer review is available for those papers requiring immediate review (for an additional fee). Complete peer review is finalized in 1-2 weeks and comments are provided to the author within 72 hours of their receipt by the editorial office. Authors are asked to submit a revised manuscript within 10-12 days. Accepted manuscripts are processed within 2-3 weeks, published online within 3 business days of final author approval, and in print in the next available issue.
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Clinical Article
doi: 10.3810/pgm.1999.11.780
Postgraduate Medicine: Volume 106: No.6
ANTIDEPRESSANT DRUG INTERACTIONS IN THE ELDERLY
Understanding the P-450 system is half the battle in reducing risks
Roger J. Cadieux, MD
Abstract: As patients age, pharmacologic treatment of depression becomes more complicated because of the increased risk of drug interactions in the elderly. Choosing an appropriate agent requires a thorough knowledge of cytochrome P-450 enzymes, which affect drug metabolism in the liver. In this article, Dr Cadieux explains the critical factors affecting antidepressant treatment in elderly patients and discusses potential and documented drug interactions of selected agents.

(read)